Multiple Copies of Tigecycline Gene Cluster <i>tmexC6D6-toprJ1b</i> in <i>Pseudomonas mendocina</i> in a Swine Farm.

ABSTRACT: Background/Objectives: The emergence and transmission of the tigecycline resistance efflux pump gene cluster tmexCD-toprJ among humans, animals and the environment have posed a serious threat to public health. The objective of this study was to characterize Pseudomonas strains carrying multiple copies of tmexC6D6-toprJ1b from a pig farm and illustrate the genetic context of tmexC6D6-toprJ1b in the NCBI database. Methods: The characterization of Pseudomonas strains FJFQ21PNM23 and FJFQ21PNM24 was determined by antimicrobial susceptibility testing, whole-genome sequencing, and RT-qPCR. Results: The tmexCD-toprJ-positive P. mendocina strains FJFQ21PNM23 and FJFQ21PNM24 were isolated from nasal swabs in a pig farm. Sequence

SUBMITTER: Wu R 

PROVIDER: S-EPMC12108250 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature