First Report of CTX-M-32 and CTX-M-101 in <i>Proteus mirabilis</i> from Zagreb, Croatia.

ABSTRACT:

Background/objectives

Proteus mirabilis is a frequent causative agent of urinary tract and wound infections in community and hospital settings. It develops resistance to expanded-spectrum cephalosporins (ESC) due to the production of extended-spectrum β-lactamases (ESBLs) or plasmid-mediated AmpC β-lactamases (p-AmpC). Here, we report the characteristics of ESBLs and p-AmpC β-lactamases encountered among hospital and community isolates of P. mirabilis in two hospitals and the community settings in Zagreb, Croatia.

Methods

Antibiotic susceptibility testing was performed using disk-diffusion and broth dilution methods. The double-disk-synergy test (DDST) and inhibitor-based test with clavulanic and cloxacillin were applied to screen for ESBLs and p-AmpC, respecti

SUBMITTER: Bedenic B 

PROVIDER: S-EPMC12108336 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature