The Application of Multiple Strategies to Enhance Methylparaben Synthesis Using the Engineered <i>Saccharomyces cerevisiae</i>.

ABSTRACT: Methylparaben (MP) is an important member of the paraben family of aromatic compounds, which is under great demand in the industrial market as an antibacterial agent, preservative, and feed additive, and also has potential application value in the preparation of bio-based polyetherester materials. However, the current chemical production method of MP has various problems, such as serious environmental pollution, its dependence on petrochemical resources, and the generation of different types of waste. It is of great significance to develop an environmentally friendly MP synthesis method via synthetic biology. In this work, Saccharomyces cerevisiae was used as the host to construct the biosynthetic pathway of MP and various metabolic engineering strategies were applied to break the b

SUBMITTER: Liu L 

PROVIDER: S-EPMC12108618 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature