Whole Genome Sequencing of <i>Kodamaea ohmeri</i> SSK and Its Characterization for Degradation of Inhibitors from Lignocellulosic Biomass.

ABSTRACT: Lignocellulosic biomass is widely recognized as a renewable resource for bioconversion. However, the presence of inhibitors such as furfural, 5-HMF, and acetic acid can inhibit cell growth, thereby affecting the overall efficiency of the bioconversion process. The studies on the degradation of lignocellulosic hydrolysate inhibitors by Saccharomyces cerevisiae have been limited. In this research, a yeast strain Kodamaea ohmeri can degrade inhibitors furfural, 5-HMF, and acetic acid, and the genome sequence of the strain was analyzed. Furthermore, the molecular detoxification mechanism of K. ohmeri SSK against lignocellulosic hydrolysate inhibitors was predicted using whole genome sequencing. Annotation based on the COG/KEGG databases identified 57 key detoxification gen

SUBMITTER: Yang YQ 

PROVIDER: S-EPMC12109290 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature