Exploring the Therapeutic Potential of <i>Rehmannia glutinosa</i>: A Network Pharmacology and Molecular Docking Analysis Across Multiple Diseases.

ABSTRACT: Rehmannia glutinosa (RG), a fundamental herb in traditional Chinese medicine belonging to the Orobanchaceae family, has been widely used for centuries due to its diverse therapeutic properties, including promoting blood circulation, enhancing immunity, managing diabetes, reducing inflammation, and supporting kidney function. Despite its traditional significance, scientific studies on RG's therapeutic mechanisms remain limited, and its underlying pharmacological pathways are not extensively elucidated. This study employed network pharmacology and molecular docking to identify RG's active compounds and investigate their therapeutic potential in allergy, anemia, diabetes, and menopause. From an initial pool of 122 compounds, 50 bioactive compounds were screened based on bioavailability

SUBMITTER: Park J 

PROVIDER: S-EPMC12110064 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature