Identifying Molecular Probes for Fluorescence-Guided Surgery in Neuroblastoma: A Systematic Review.

ABSTRACT: Background/Objectives: Targeted and non-targeted fluorescent molecular probes (FMPs) can be used intra-operatively to visualise tumour tissue. Multiple probes have been clinically approved for fluorescence-guided surgery (FGS) in adult oncology, and the translation of these technologies to paediatric neuroblastoma may provide novel strategies for optimising tumour resection whilst minimising morbidity. We aimed to identify clinically approved FMPs with potential utility for FGS in neuroblastoma. Methods: A systematic review of the literature was performed in accordance with the PRISMA guidelines (PROSPERO CRD42024541623). PubMed and Web of Science databases were searched to identify studies investigating clinically approved FGS probes and/or their targets in the context of ne

SUBMITTER: Hennessy M 

PROVIDER: S-EPMC12110316 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature