Genome-Wide Identification and Expression Analysis of the YTH Domain-Containing Protein Gene Family in <i>Salvia miltiorrhiza</i>.

ABSTRACT: YTH domain-containing proteins act as the primary readers of N⁶-methyladenosine (m⁶A), playing an important role in plant development and stress responses. However, little is known about the YTH proteins in medicinal plants. Genome-wide identification of the YTH gene family in the medicinal model plant, Salvia miltiorrhiza Bunge, identified a total of nineteen SmYTH genes from five chromosomes, with SmYTH8-SmYTH19 clustered on chromosome 8. Phylogenetic analysis showed that SmYTH proteins belong to the YTHDF category. No YTHDC members were identified. Conserved domain identification, amino acid sequence alignment, and phase separation prediction revealed that SmYTH1-SmYTH4 exhibited the characteristic m⁶A reader pro

SUBMITTER: Wang C 

PROVIDER: S-EPMC12110915 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature