Enhancing the Potential of Microhaplotypes for Forensic Applications: Insights from Afghan and Somali Populations.

ABSTRACT: Microhaplotypes (MHs) are a novel class of genetic markers, exhibiting features that position them as an alternative to STRs and SNPs in addressing challenges commonly encountered in forensic investigations. Additionally, MHs can also offer valuable insights for ancestry inference. However, due to the novelty of MHs, extensive research in different global populations is required before implementation in forensic casework and general research. In this study, individuals from Afghanistan and Somalia were characterized with the Ion AmpliSeq™ MH-74 Plex Research Panel previously developed for forensic genetic purposes. A total of 84 Afghan and 89 Somalian samples were sequenced on the Ion GeneStudio™ S5 System. This led to the identification of 32 and 42 single nucleotide variants in the Afgha

SUBMITTER: Rodrigues P 

PROVIDER: S-EPMC12111283 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature