The global health burden of pediatric chronic kidney disease: An analysis of the Global Burden of Disease database from 1990 to 2021.

ABSTRACT:

Background

Chronic kidney disease (CKD) poses a significant global health challenge; however, its burden on pediatric populations remains underexplored. This study assesses the incidence, prevalence, mortality, and disability-adjusted life years (DALYs) of pediatric CKD attributable to type 1 diabetes mellitus, type 2 diabetes mellitus, hypertension, glomerulonephritis, and congenital anomalies of the kidney and urinary tract from 1990 to 2021.

Methods

Data were extracted from the Global Burden of Disease (GBD) 2021 database. CKD burden was stratified by etiology, age, sex, sociodemographic index (SDI), and geography. Average annual percentage changes (AAPCs) in incidence, prevalence, mortality, and DALYs were calculated.

Results

Globally, CKD-related mortality and DA

SUBMITTER: Raina M 

PROVIDER: S-EPMC12111535 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature