Unveiling the Chemical Composition, Antioxidant, and Antimicrobial Potentials of <i>Foeniculum vulgare</i> Mill: A Combined In Vitro and In Silico Approach.

ABSTRACT: This study on Foeniculum vulgare Mill., derived from seeds collected in Meknes (Morocco), evaluates in vitro and in silico the therapeutic potential of its extracts and essential oil through a comprehensive analysis of its phytochemical composition, as well as its antioxidant and antimicrobial activities. Aqueous extracts (E0), hydroethanolic extract (E1) obtained via Soxhlet, decoction (E2), and essential oil (EO) obtained through hydrodistillation were analyzed using HPLC/UV-ESI-MS and GC-MS, revealing a richness in phenolic and terpenic compounds. The quantification of total polyphenols, flavonoids, and tannins in aqueous and organic extracts was performed using spectrophotometric methods. Antioxidant activity was assessed through three methods: DPPH, FRAP, and Total Antioxidant

SUBMITTER: Moumen BE 

PROVIDER: S-EPMC12111592 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature