Efficacy, Safety, and Cost-Effectiveness of "Internet + Pharmacy Care" Via the Alfalfa App in Warfarin Therapy Management After Cardiac Valve Replacement: Randomized Controlled Trial.

ABSTRACT:

Background

Anticoagulation management is important in preventing complications in patients undergoing cardiac valve replacement. The development of mobile apps offers new opportunities for the management of long-term anticoagulants. However, there is a lack of randomized controlled trials evaluating the effectiveness, safety, cost-effectiveness, and user demand for internet-based anticoagulation management.

Objective

This study aimed to evaluate the efficacy, safety, and cost-effectiveness of a 3-month warfarin dose adjustment mobile app Alfalfa compared to offline management in patients postcardiac valve replacement. We also explored the app's feasibility on user satisfaction and demand.

Methods

This study was a randomized controlled trial with assessments conducted

SUBMITTER: Qian Y 

PROVIDER: S-EPMC12112255 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature