Arsenic Stress Resistance in the Endophytic Fungus <i>Cladosporium cladosporioides</i>: Physiological and Transcriptomic Insights into Heavy Metal Detoxification.

ABSTRACT: This study aims to evaluate the tolerance of an endophytic fungus isolated from the fibrous roots of Gentiana yunnanensis Franch. to arsenic (As) and elucidate the underlying physiological and molecular mechanisms. The filamentous fungus is identified as Cladosporium cladosporioides based on morphological characteristics and phylogenetic tree analysis, belonging to the family Moniliaceae and Phyla Hyphomycetes. The tolerance of C. cladosporioides to As(V) was assessed by measuring its biomass under varying concentrations of As(V). The fungus exhibited remarkable As(V) tolerance, with an EC₅₀ value of 2051.94 mg/L, and accumulated high concentrations of As in its mycelium. Subcellular distribution analysis revealed that As was predominantly localized in the c

SUBMITTER: You XX 

PROVIDER: S-EPMC12112881 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature