Hypereosinophilic Syndrome Presenting with Digestive Symptoms in Pediatric Patients: A Portuguese Tertiary Hospital Case Series.

ABSTRACT:

Introduction

Hypereosinophilic syndrome (HES) is an uncommon disorder characterized by persistent peripheral eosinophilia and involvement of different organs. It is rare in pediatric ages.

Cases presentation

We present 3 pediatric patients diagnosed with HES exhibiting digestive symptoms. Clinical records, laboratory results, imaging studies, and treatment plans were systematically collected and analyzed. All patients underwent an extensive etiological investigation to exclude infectious, autoimmune, and tumoral causes. Treatment with corticosteroids resulted in symptomatic and analytical improvement in all patients.

Conclusion

This case series highlights the complexity of pediatric HES presenting with digestive manifestations. The diverse clinical presentation unders

SUBMITTER: Sousa M 

PROVIDER: S-EPMC12113416 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature