Extra-Thyroidal Impacts of Serum Iodine Concentrations During Early Pregnancy on Metabolic Profiles and Pregnancy Outcomes: Prospective Study Based on Huizhou Mother-Infant Cohort.

ABSTRACT: Objectives: This study aimed to test the extra-thyroidal impacts of maternal serum iodine concentrations (SICs) on metabolic factors and subsequent pregnancy outcomes. Methods: Single pregnant women aged 18-49 years were recruited during their first prenatal visits. SICs at first trimester (T1) were tested by ICP-MS. Metabolic factors [body mass index (BMI), fat %, glucose, lipids, uric acid, and blood pressure] were measured, and composite indices [the triglyceride-glucose (TyG) index, TyG-BMI, and the Framingham steatosis index (FSI)] were estimated. Obstetric and birth outcomes were retrieved from the hospital information system, including gestational diabetes (GDM), gestational hypertension (GH), fetal distress, postpartum hemorrhage, premature rupture of membrane, small

SUBMITTER: Liu Z 

PROVIDER: S-EPMC12113788 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature