Emergence of NDM-1- and OXA-23-Co-Producing <i>Acinetobacter baumannii</i> ST1 Isolates from a Burn Unit in Spain.

ABSTRACT: The global emergence of carbapenem-resistant Acinetobacter baumanii (CRAB) represents a significant public health threat. In the summer of 2022, a polyclonal CRAB outbreak occurred in our hospital, marking the first detection of an NDM-1 plus OXA-23 co-producing A. baumannii strain in Spain. The aim of this study was to phenotypically and genotypically characterize the clonal spread of NDM-1 and OXA-23 co-producing A. baumannii isolates and to describe the infection control measures implemented to contain the outbreak. Patients with multidrug-resistant A. baumannii isolates (July 2022-May 2023) were included in the study. Isolates were identified via MALDI-TOF, and antimicrobial susceptibility was tested using a broth microdilution method (DKMGN SensititreTM pan

SUBMITTER: Hidalgo E 

PROVIDER: S-EPMC12113993 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature