Chemical Profiling and Assessment of Analgesic and Anti-Inflammatory Activity of <i>Ammoides verticillata</i> Essential Oil: In Vitro, In Vivo, and In Silico Studies.

ABSTRACT: Background/Objectives: Essential oils are increasingly recognized for their therapeutic potential, yet Ammoides verticillata essential oil (AVEO) remains relatively unexplored, particularly for its anti-inflammatory and analgesic properties. This study aimed to profile AVEO's chemical composition and evaluate its antioxidant, anti-inflammatory, and analgesic effects, with a focus on its novel pharmacological actions. Methods: The chemical composition of AVEO was determined using GC-MS analysis, and antioxidant capacity was assessed through in vitro assays. Furthermore, the anti-inflammatory potential was investigated using a carrageenan-induced paw edema model in rats, complemented by the inhibition assays of cyclooxygenase (COX) enzymes. The analgesic effects were eva

SUBMITTER: Derardja I 

PROVIDER: S-EPMC12114468 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature