Genomic and Phenotypic Characterization of a Novel Virulent Strain of <i>Cyvirus cyprinidallo</i>2 Originating from an Outbreak in The Netherlands.

ABSTRACT: Cyvirus cyprinidallo2 (CyHV-2) is the causative agent of herpesviral hematopoietic necrosis in several economically important farmed freshwater fish species of the genus Carassius. Despite several CyHV-2 strains being isolated and fully sequenced, there is a lack of detailed characterization and consistent information on strains that exhibit high virulence in adult goldfish through viral challenge by immersion, particularly in the context of European strains and host populations. Strains that can cause highly virulent disease via this inoculation route are much more compatible with experimental designs that are representative of natural infection; thus, their utilization provides greater biological relevance. Consequently, in this study, we isolated three novel strains of CyH

SUBMITTER: He B 

PROVIDER: S-EPMC12116052 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature