A "proto" type galectin expressed in striped bass (<i>Morone saxatilis</i>) tissues is released to epidermal mucus and binds to bacterial and mucus glycans.

ABSTRACT: Like all aquatic vertebrates and invertebrates, teleost fish are subject to the constant pressure of bacterial, fungal, and parasitic organisms present in the environmental interface that can potentially cause disease. Numerous defense molecules, including galectins, have been isolated from the skin and gut tissues of several marine and freshwater fish species. To provide new insights into the potential role(s) of galectins in the teleost fish innate immune system, we carried out studies on the striped bass (Morone saxatilis), a keystone fish species in Chesapeake Bay. We purified from epidermal skin mucus, and skin and muscle tissue, a 15-kDa galectin that we designated Msgal1-L1 (M. saxatilis galectin1-like protein 1). Both the transcript sequence and gene organization of M

SUBMITTER: Henrikson DE 

PROVIDER: S-EPMC12116657 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature