A bacteriolysin of Lactococcus carnosus is potentially involved in mediating contact-dependent antagonism against Listeria monocytogenes.

ABSTRACT: Lactococcus carnosus CNCM I-4031 is a psychrotrophic lactic acid bacterium used for the biopreservation of seafood. It effectively inhibits the growth of spoilage and pathogenic bacteria, such as Listeria monocytogenes, through an atypical mechanism that relies on direct cell-to-cell contact, without producing conventional antimicrobial compounds like diffusible bacteriocins, which are released into the environment to eliminate nearby cells during interbacterial competition. However, the precise molecular mechanism behind this bacterial interaction remains to be fully understood. In this study, Label-free LC-MS/MS shotgun proteomics and gene expression analysis were used to examine cell envelope protein expression in L. carnosus when cultivated alone and in co-culture with L. monocytogenes

SUBMITTER: Tareb R 

PROVIDER: S-EPMC12116727 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature