¹H, ¹³C, ¹⁵N and ³¹P chemical shift assignment of the first stem-loop Guanidine-II riboswitch from Escherichia coli.

ABSTRACT: A comprehensive understanding of RNA-based gene regulation is a fundamental aspect for the development of innovative therapeutic options in medicine and for a more targeted response to environmental problems. Within the different mechanisms of RNA-based gene regulation, riboswitches are particularly interesting as they change their structure in response to the interaction with a low molecular weight ligand, often a well-known metabolite. Four distinct classes of riboswitches recognize the very small guanidinium cation. We are focused on the Guanidine-II riboswitch with the mini-ykkC motif. We report here the assignment of the ¹H, ¹³C, ¹⁵N and ³¹P chemical shifts of the 23 nucleotide-long sequence of the first stem-loop of the Guanidine-II riboswi

SUBMITTER: Koob T 

PROVIDER: S-EPMC12117010 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature