Alzheimer's and dementia: Diagnosis, assessment, and disease monitoring global, regional, and national burden of Alzheimer's disease and other dementias (ADODs) and their risk factors, 1990-2021: A systematic analysis for the Global Burden of Disease study 2021.

ABSTRACT:

Introduction

Aging populations globally lead to growing challenges in Alzheimer's disease and other dementias (ADODs). Tracking ADODs aids health strategies. To describe global, regional, and national incidence, prevalence, death, and disability-adjusted life years (DALYs) of ADODs in 2021, and analyze changes from 1990 to 2021.

Methods

We analyzed ADODs using the 2021 Global Burden of Disease database, calculating estimated annual percentage change (EAPC), applying Joinpoint regression, and assessing risk factors.

Results

Between 1990 and 2021, ADOD incidence, prevalence, deaths, and DALYs increased significantly. DALYs grew 295.45% and fatalities grew 167.72%. Age-standardized rates (ASRs) rose for both genders, with women generally higher but men showing steeper in

SUBMITTER: Wang F 

PROVIDER: S-EPMC12117199 | biostudies-literature | 2025 Apr-Jun

REPOSITORIES: biostudies-literature