Oxygen saturation targets in neonatal care: A narrative review.

ABSTRACT: Optimal oxygenation requires the delivery of oxygen to meet tissue metabolic demands while minimizing hypoxic pulmonary vasoconstriction and oxygen toxicity. Oxygen saturation by pulse oximetry (SpO₂) is a continuous, non-invasive method for monitoring oxygenation. The optimal SpO₂ target varies during pregnancy and neonatal period. Maternal SpO₂ should ideally be ≥95 % to ensure adequate fetal oxygenation. Term neonates can be resuscitated with an initial oxygen concentration of 21 %, while moderately preterm infants require 21-30 %. Extremely preterm infants may need higher FiO₂, followed by titration to desired SpO₂ targets. During the NICU course, extremely preterm infants managed with an 85-89 % SpO₂ target compared to

SUBMITTER: Nguyen TC 

PROVIDER: S-EPMC12121305 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature