Paediatric glaucoma in Stickler syndromes: a comprehensive review of prevalence, comorbidities and outcomes.

ABSTRACT:

Importance

This review explores the prevalence, diagnostic challenges, associated comorbidities, and potential complications of early-onset glaucoma in individuals with Stickler syndrome. By addressing these aspects, this review aims to enhance clinical awareness, improve patient outcomes and highlight research opportunities within the paediatric Stickler syndrome population.

Methods and results

Of 185 unique studies, 51 duplicates were removed, leaving 15 studies for analysis. The review included data from 679 patients, of whom 82 were reported as being diagnosed with glaucoma, yielding an overall prevalence of 12.1%. The prevalence was 7.5% in patients aged 0-10 years and remained stable through age 20. It then increased to 18% in patients aged 21-40 years, before slightly

SUBMITTER: Gocuk SA 

PROVIDER: S-EPMC12121566 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature