Guidelines for the management of emergencies and critical illness in pediatric and adult patients with sickle cell disease.

ABSTRACT: Forty-two questions were evaluated concerning management of emergencies and critical illnesses in paediatric and adult patients with sickle cell disease. The assessment covered the following areas: patient referral, vaso-occlusive crisis, acute chest syndrome, transfusion therapy, and priapism. The patient referral category included guidelines for admission to intensive care unit and management at specialized reference centers. The vaso-occlusive crisis topic encompassed pain management, hydration, incentive spirometry, and target oxygen saturation levels. For acute chest syndrome, the focus areas included imaging techniques such as lung ultrasound, computed tomography scans, and echocardiography; treatment with systemic corticosteroids; non-invasive ventilation; prophylactic and therapeut

SUBMITTER: Mekontso Dessap A 

PROVIDER: S-EPMC12123041 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature