Impact of manganese and metal mixtures in blood, hair, and soil on child adaptive behaviors in Southeast Side Chicago.

ABSTRACT:

Background

Manganese (Mn) is essential in growth and development, yet higher levels of Mn are associated with deficits in neurodevelopment. Elevated air Mn was identified near Mn alloy processing facilities in Southeast Side Chicago resulting in community concern about child exposure and health.

Methods

Blood, hair, and soil samples were collected and analyzed for multiple metals for children ages 7-17 years and a parent/primary caregiver completed surveys. We used generalized estimating equations to assess associations between metals and the Adaptive Behavior Assessment System 3rd Edition (ABAS-3) scores. Sensitivity analyses were conducted to determine effect modification by child sex on associations between metals and ABAS-3 scores. Bayesian kernel machine regression was

SUBMITTER: Kim C 

PROVIDER: S-EPMC12124939 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature