All-Cause Mortality is Higher in Generalized Pustular Psoriasis (GPP) than Plaque Psoriasis and the General Population: A US-Based Claims Analysis.

ABSTRACT:

Background

Limited literature exists on the mortality burden of generalized pustular psoriasis (GPP) in the US.

Objective

To compare all-cause mortality among patients with GPP with matched populations of patients with plaque psoriasis (PsO) and the general population in the US.

Methods

An observational study was conducted using US claims data collected between January 1, 2016 and December 31, 2019. All-cause mortality was evaluated at 365 days post-index and at maximum follow-up in the following cohorts: GPP-only, Plaque-PsO-only, GPP + PsO, All-GPP, and general population. Propensity score matching was used to balance covariates between cohorts. The index date was the first medical claim for GPP (ICD-10 code L40.1) or PsO (L40.0),

SUBMITTER: Gottlieb AB 

PROVIDER: S-EPMC12125009 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature