Development and validation of a prediction model for cholangitis after percutaneous transhepatic cholangioscopic lithotripsy.

ABSTRACT: Cholangitis is a common complication of percutaneous transhepatic cholangioscopic lithotripsy (PTCSL) for hepatolithiasis, but risk assessment tools are lacking. This study aimed to identify predictors of cholangitis after PTCSL and develop a predictive nomogram. This retrospective study analysed 245 patients who underwent 450 PTCSL sessions between 1 January 2016 and 1 January 2024. All sessions demonstrating cholangitis complications were classified into the cholangitis group, while the remaining sessions were classified into the non-cholangitis group. All the sessions were divided into training and validation sets. Least absolute shrinkage and selection operator (LASSO) analysis was conducted to preliminarily select predictors of cholangitis complications. Multivariable logistic regress

SUBMITTER: Cheng L 

PROVIDER: S-EPMC12125099 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature