Evidence for peroxisomal redundancy among the glucose-6-phosphate dehydrogenase isoforms of Arabidopsis thaliana.

ABSTRACT: The oxidative pentose phosphate pathway (OPPP) plays an important role in the generation of reducing power in all eukaryotes. In plant cells, the OPPP operates in several cellular compartments, but as full cycle only in the plastid stroma where it is essential. As suggested by our recent results, OPPP reactions are also mandatory inside peroxisomes, at least during fertilization. For the first enzyme of the OPPP, glucose-6-phosphate dehydrogenase (G6PD), we previously showed that one Arabidopsis isoform (G6PD1) can be directed to peroxisomes under specific circumstances. Since g6pd1 knock-out plants are viable, we aimed at elucidating potential redundancy regarding peroxisomal targeting among the other G6PD isoforms. Localization studies of so far cytosolic annotated G6PD5 and G6PD6 (both

SUBMITTER: Linnenbrugger L 

PROVIDER: S-EPMC12125578 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature