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ABSTRACT: Background
The relationship between the Triglyceride-Glucose (TyG) index and periodontitis remains unclear. This study aims to elucidate this relationship using data from two large population-based surveys.Methods
Datasets from NHANES (2009-2014) and KNHANES (2007-2018, except for 2011) were utilized. We applied multivariate logistic regression, stratified analysis, restricted cubic splines (RCS), and subgroup analyses to examine the correlation between the TyG index and periodontitis risk. The predictive value of the TyG index was assessed using receiver operating characteristic (ROC) curves. Mediation analyses investigated variables mediating this relationship.Results
The NHANES and KNHANES cohorts included 2,511 and 16,239 participants with periodontitis, respect
SUBMITTER: Huang J
PROVIDER: S-EPMC12127200 | biostudies-literature | 2025
REPOSITORIES: biostudies-literature