Outcome Measures in Dystrophic Calcinosis Cutis: A Systematic Review.

ABSTRACT:

Background

Calcinosis cutis is a skin condition characterized by calcium salt deposition in the skin and subcutaneous tissues, significantly affecting patients' QOL. Owing to its rarity and lack of standardized outcome measures, there are no approved medications.

Objective

This systematic review aims to summarize clinically relevant outcome measures used to assess dystrophic calcinosis cutis.

Methods

A systematic literature search was conducted in Medline, Embase, and Web of Science. Studies were included if they reported clinical outcomes assessing dystrophic calcinosis cutis. Data extraction and risk of bias assessment were performed independently by 2 researchers using standardized tools.

Results

Twenty-six studies met inclusion criteria, with the majority b

SUBMITTER: Foster J 

PROVIDER: S-EPMC12127648 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature