Carbapenem-resistance in Acinetobacter baumannii: prevalence, antibiotic resistance profile and carbapenemase genes in clinical and hospital environmental strains.

ABSTRACT:

Background

Acinetobacter baumannii, a Gram-negative member of the ESKAPE pathogen group, is known to develop resistance to several antibiotics rapidly, and carbapenem-resistant A. baumannii (CRAB) is highly implicated in life-threatening infections, especially within hospital settings.

Objectives

This study detected CRAB in clinical and hospital-environmental samples, evaluated the antibiotic resistance patterns and screened for prevalent carbapenemase genes in isolates from a hospital in Southwest Nigeria.

Methods

A total of 150 clinical and hospital environmental samples were analysed using culture-dependent and molecular methods for the detection of Acinetobacter baumannii. Antibiotic susceptibility test was done using the Kirby-Bauer disk diffusion technique. Phen

SUBMITTER: Adeyemi FM 

PROVIDER: S-EPMC12128347 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature