Transcutaneous auricular vagus nerve stimulation prevents postoperative delirium in elderly patients (VNSTAR): protocol for a multicentre, randomised controlled trial.

ABSTRACT:

Introduction

Postoperative delirium (POD) is a common complication in elderly patients and is closely associated with delayed recovery, prolonged hospital stays, increased mortality rates and increased medical expenses. Vagus nerve stimulation, a novel technique in the field of neuroscience, has demonstrated remarkable therapeutic potential in improving neurocognitive disorders. However, its applicability in ameliorating neurocognitive dysfunctions that arise during the perioperative period remains unclear. To date, no large prospective, randomised controlled studies have explored the effects of vagus nerve stimulation on POD.

Method and analysis

This study is a multicentre, double-blind, parallel, randomised controlled trial. It aims to explore the preventative effects of t

SUBMITTER: Wu Y 

PROVIDER: S-EPMC12128425 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature