Effectiveness of aerobic physical exercise on depression symptoms in adults: A protocol for developing a systematic review and meta-analysis of randomized clinical trials.

ABSTRACT:

Background

Depression is a chronic condition that affects millions of people and requires effective interventions. Studies suggest that aerobic exercise can improve mental health and reduce depression symptoms, despite variations in exercise type and intensity.

Objective

This article presents a protocol for conducting a systematic review with meta-analysis, aimed at investigating the effects of aerobic exercise on reducing depression symptoms in adults.

Methods

This is a systematic review protocol, which will follow the PRISMA-P 2020 guidelines and has been registered in PROSPERO (no. CRD42024592700). The study search will be conducted in six databases: BVS, Cochrane library, Embase, Epistemonikos, PubMed and SPORTDiscus, using MeSH-based descriptors. Studies will be

SUBMITTER: de Souza LN 

PROVIDER: S-EPMC12129328 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature