Pandemic human-associated extended-spectrum β-lactamase-producing Escherichia coli lineages of ST38, ST131 and ST141 identified in Viennese dogs.

ABSTRACT:

Objectives

To assess the prevalence of ESBL Enterobacteriaceae among dogs attending a veterinary clinic in Vienna, characterize the isolates in terms of antimicrobial resistance, virulence and phylogenetic relationships.

Methods

Faecal samples of 88 dogs were streaked on selective plates, species were identified by MALDI-ToF MS, tested for resistance by a combination disk test and VITEK 2®, whole genome-sequenced, bioinformatically genotyped, phylogenetically analysed and screened for resistance and virulence genes.

Results

ESBL Escherichia coli carriage rate was 14.8% (95% CI: [8.1-23.9]). No carbapenem resistance was found, but 53.8% of the isolates were classified genotypically as multi-drug resistant. Phylogenetic analyses revealed that half of the isolates belong

SUBMITTER: Saria P 

PROVIDER: S-EPMC12129576 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature