Prevalence of Epilepsy in Frontotemporal Dementia and Timing of Dementia Diagnosis.

ABSTRACT:

Importance

Previous studies have described a potential association between epilepsy and frontotemporal dementia (FTD), but no systematic data are available.

Objective

To determine whether epilepsy is more prevalent in patients with FTD than in healthy controls (HCs) or patients with Alzheimer disease (AD).

Design, setting, and participants

In this case-control study, we compared the prevalence of epilepsy and purchases of antiseizure medicines (ASMs) among patients with FTD, matched HCs, and patients with AD from 2 early-onset dementia diagnostics centers in the same geographic regions of Finland. AD or FTD diagnoses were made between January 1, 2010, and December 31, 2021. Data were analyzed from January 26, 2024, to January 16, 2025.

Main outcomes and measures

SUBMITTER: Kilpelainen A 

PROVIDER: S-EPMC12131175 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature