Molecular epidemiology and clinical features of <i>Klebsiella variicola</i> bloodstream infection compared with infection with other <i>Klebsiella pneumoniae</i> species complex strains.

ABSTRACT: Klebsiella variicola is an emerging pathogen within the Klebsiella pneumoniae species complex, and its clinical and microbiological characteristics remain poorly understood. This retrospective case-control study analyzed 252 patients with bloodstream infections caused by K. pneumoniae species complex, including 60 with K. variicola infection, to elucidate these characteristics. Our study showed no significant differences in clinical outcomes, such as 30-day mortality, between K. variicola and K. pneumoniae. However, a significant difference was found in the rate of harboring [peg-344, iucA, and rmpA] genes, which are associated with virulence in K. pneumoniae, suggesting that K. variicola may be generally less vir

SUBMITTER: Ohno T 

PROVIDER: S-EPMC12131774 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature