Investigating the profile of patients with idiopathic inflammatory myopathies in the post-COVID-19 period.

ABSTRACT: The 2019 coronavirus disease (COVID-19) pandemic has changed the characteristics of many diseases. It remains unclear whether idiopathic inflammatory myopathies (IIMs) exhibit distinct phenotypes in the context of COVID-19. This retrospective study analyzed patients with IIMs admitted to West China Hospital from January 2022 to December 2023. Among them, 171 had a history of COVID-19 (prior COVID-19 [PC]), while 121 did not (no prior COVID-19 [NPC]). Medical histories, lab tests, and echocardiography data were compared. The PC group exhibited a greater incidence of cardiac damage, including a greater proportion of cardiac injury (P = 0.016), clinical diagnosis of myocarditis (P = 0.02), palpitation (P = 0.031), and Myositis Activity Assessment Visual Analog Scale/Myosi

SUBMITTER: Cheng L 

PROVIDER: S-EPMC12131821 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature