Comparative genomic analysis of 255 <i>Oenococcus oeni</i> isolates from China: unveiling strain diversity and genotype-phenotype associations of acid resistance.

ABSTRACT: Oenococcus oeni, the only species of lactic acid bacteria capable of fully completing malolactic fermentation under challenging wine conditions, continues to intrigue researchers owing to its remarkable adaptability, particularly in combating acid stress. However, the mechanism underlying its superior adaptation to wine stresses still remains elusive due to the lack of viable genetic manipulation tools for this species. In this study, we conducted genomic sequencing and acid resistance phenotype analysis of 255 O. oeni isolates derived from diverse wine regions across China, aiming to elucidate their strain diversity and genotype-phenotype associations of acid resistance through comparative genomics. A significant correlation between phenotypes and evolutionary relationships

SUBMITTER: Chi W 

PROVIDER: S-EPMC12131864 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature