Determining the Efficacy, Feasibility, and Impact of Storage Conditions on At-Home Blood Collection Kits for Proteomic Studies.

ABSTRACT: At-home blood collection kits have the potential to greatly increase the efficiency of blood collection for diagnostic or research purposes by reducing the cost and burden on participants, researchers, or physicians and eliminating the need for a phlebotomist, specialized equipment, and on-site processing. These kits have shown to be effective for studying specific blood metabolites and proteins, but for analyses targeting the entire proteome, their effectiveness is unknown. For this study, data on human serum proteome was compared when blood was capillary-collected with a Tasso+ device (Tasso Inc.) versus the gold-standard venous samples drawn by a trained phlebotomist. Analyses were conducted using the SomaScan 7K assay (SomaLogic Inc.), which assesses the levels of nearly 7,600 serum pr

SUBMITTER: Scranton C 

PROVIDER: S-EPMC12132123 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature