Quantifying the role of importation on sustained malaria transmission in a low-to-moderate burden region of Southwest Uganda.

ABSTRACT:

Background

Parasite importation remains a critical challenge to malaria elimination efforts. The extent to which human travel contributes to sustained transmission in low-to-moderate burden areas of highly endemic African countries is poorly understood.

Methods

We conducted a 14-month longitudinal cohort study in Kamwezi subcounty in Southwest Uganda, an area targeted for malaria elimination where sustained transmission poses challenges. A total of 1,918 individuals from 400 households were enrolled and followed bi-monthly. Travel histories, malaria episodes, and household characteristics were collected through structured surveys. Incident malaria was captured via passive case detection at the local health facility and self-report. Multilevel logistic regression models estim

SUBMITTER: Epstein A 

PROVIDER: S-EPMC12132150 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature