Temporal coding carries more stable cortical visual representations than firing rate over time.

ABSTRACT: The brain's ability to stably represent recurring visual scenes is crucial for behavior. Previous studies have used slow dynamic (1-5 seconds) rate code measurements to study visual tuning, revealing varying degrees of gradual activity changes over time or "representational drifts." However, it remains unclear if there is an underlying neural code that maintains the encoding of information stable over time. In this study, we extracted structures in fast (tens of milliseconds) temporal responses and explored the role of such temporal codes in supporting the stability of visual representations. We tracked the spiking activity of the same visual cortical populations in male mice for 15 consecutive days using custom-developed, large-scale, ultraflexible electrode arrays. Across various types o

SUBMITTER: Zhu H 

PROVIDER: S-EPMC12132223 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature