Racial and Ethnic Disparities in Cardiotoxicity in Patients With Cancer Treated With Anthracyclines.

ABSTRACT:

Background

Cardiotoxicity in patients with cancer treated with anthracyclines is associated with increased morbidity and mortality. We aimed to examine the incidence of and risk factors for cardiotoxicity in a racially and ethnically diverse cohort with cancer treated with anthracyclines.

Methods

We included consecutive adult patients who underwent anthracycline-based chemotherapy from 2016 to 2019 for any type of cancer. The end point was the development of cardiotoxicity (defined as clinical heart failure or drop in left ventricular ejection fraction ≥10% to ≤50%).

Results

A total of 743 individuals were included (28.0% Non-Hispanic [NH] White, 30.5% NH Black, 38.5% Hispanic, 3.0% Asian). Hypertension, diabetes, hyperlipidemia, obesity, and low socioeconomic status

SUBMITTER: Zhang L 

PROVIDER: S-EPMC12132864 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature