Pairing between homologous sequences on the X and chromosome 3 in Drosophila male meiosis.

ABSTRACT: Pairing between sex chromosomes in male Drosophila normally occurs at intergenic spacer (IGS) sequences within the tandemly repeated rDNA genes that are located proximally in the heterochromatin on both the X and Y. Pairing is not limited to these sequences, however, and can also occur with high fidelity between the X and segments of X euchromatin that have been translocated to the Y. Such euchromatic pairings can lead to segregation of the X and Y, even when the X is rDNA-deficient, suggesting X-Y conjunction remains at these euchromatic sequences until anaphase I. From these previous observations, however, it was unclear if conjunction occurred directly at euchromatic sequences, or if conjunction occurred due to residual IGS repeats remaining on the rDNA-deleted X. Here, to ask if pairin

SUBMITTER: Hylton CA 

PROVIDER: S-EPMC12135174 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature