Symptom prevalence in patients with advanced heart failure and its association with quality of life and activities of daily living.

ABSTRACT:

Background

Quality of life (QOL) and functional status are two key outcomes for patients with advanced heart failure (HF). We examined the association of eleven symptoms with QOL and functional status impairment in patients with advanced HF.

Methods and results

This was a retrospective analysis of baseline data from a multi-center, cluster-randomized controlled trial (NCT01459744) which enrolled patients with an implanted cardioverter-defibrillator and advanced HF at high-risk for mortality. Study instruments included the Condensed Memorial Symptom Assessment Scale, the Kansas City Cardiomyopathy Questionnaire QOL subscale, and the number of activities of daily living (ADL) patients had difficulties with. The study included 413 subjects. In generalized linear models which we

SUBMITTER: Blum M 

PROVIDER: S-EPMC12135210 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature