Implications of sociodemographic and clinical factors on symptom burden: Age-specific survivorship care in the primary central nervous system tumor population.

ABSTRACT:

Background

This analysis aims to provide insight into differences in symptom burden and general health status between young adults (YA; 18-39 years old) and older adults (OA; ≥40 years old) with primary central nervous system tumors.

Methods

Data were retrospectively analyzed from the National Cancer Institute Neuro-Oncology Branch's Natural History Study (NCT02851706 PI: T.S. Armstrong) to determine differences in patient-reported outcomes (general health status [EQ-5D-3L], symptom burden [MDASI-BT and MDASI-SP], anxiety/depression [Patient-Reported Outcomes Measurement Information System], and perceived cognition [Neuro-QOL]) and demographic and clinical data using chi-square, one-way ANOVA, and Student's t-tests. Linear regression with backward elimination determin

SUBMITTER: Robins KR 

PROVIDER: S-EPMC12137206 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature