Impaired right atrial function preceding right ventricular systolic dysfunction: clinical utility and long-term prognostic value in pulmonary hypertension.

ABSTRACT:

Objectives

Pulmonary hypertension (PH) in patients with right ventricular systolic dysfunction (RVSD) is associated with a poor prognosis. This study assessed the characteristics of right atrial (RA) function using cardiac magnetic resonance feature tracking (CMR-FT) before RVSD onset and evaluated the long-term prognostic significance of these characteristics.

Materials and methods

A total of 96 PH patients, including 36 without RVSD (PH-nonRVSD) and 60 with RVSD (PH-RVSD), were compared to 20 healthy controls (HCs). The RA reservoir, conduit, booster pump functions, and the right ventricular global longitudinal strain (RVGLS) were evaluated. Ventricular morphological and functional parameters of the RA and right ventricle (RV) were also acquired.

Results

Compared wi

SUBMITTER: Yang F 

PROVIDER: S-EPMC12137862 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature