Early rhythm control compared to rate control in atrial fibrillation - A systematic review, meta-analysis, and meta-regression.

ABSTRACT:

Background

This meta-analysis aimed to compare the effectiveness of early rhythm control to rate control, and whether catheter ablation derived more benefit compared to other methods of rhythm control.

Methods

A comprehensive literature search was conducted on PubMed, SCOPUS, and EuropePMC up to July 2, 2024. The primary outcome of this study was major adverse cardio-cerebrovascular events (MACCE), defined as a composite of mortality, stroke/systemic embolism, heart failure hospitalization (HFH), and acute coronary syndrome (ACS) during the follow-up period. Outcome measures were adjusted hazard ratios (aHR).

Results

A total of 504,124 patients from 11 studies were included in this systematic review and meta-analysis. Early rhythm control was significantly associated

SUBMITTER: Hermanto K 

PROVIDER: S-EPMC12138061 | biostudies-literature | 2025 Mar-Apr

REPOSITORIES: biostudies-literature