FimX regulates type IV pilus localization via the Pil-Chp chemosensory system in <i>Acinetobacter baylyi</i>.

ABSTRACT: Type IV pili (T4P) are widespread dynamic appendages required for diverse prokaryotic behaviors including twitching motility, biofilm formation, and DNA uptake leading to natural transformation. Although the components involved in T4P assembly and dynamics are largely conserved across divergent clades of bacteria, the mechanisms underlying T4P function and regulation differ significantly and remain poorly characterized outside of a select few model organisms. One understudied characteristic of T4P includes the spatial organization of T4P envelope-spanning nanomachines and how organizational patterns contribute to single cell behaviors. The bacterial species Acinetobacter baylyi localizes its T4P nanomachines in a unique pattern along the long axis of the cell, making it a robust mod

SUBMITTER: Ellison TJ 

PROVIDER: S-EPMC12139848 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature