Clinical characteristics of gastrointestinal stromal tumors with lymph node metastasis: a retrospective single-center study.

ABSTRACT:

Background

Lymph node metastasis (LNM) of gastrointestinal stromal tumors (GISTs) rarely occurs, and lymphadenectomy is not routinely performed in GIST resection. To date, the relevant characteristics and prognosis of GIST patients with LNM are not well known.

Methods

From January 2010 to December 2021, GIST patients who underwent lymph node resection were enrolled from a GIST referral center. All patients were divided into either the LN- group (GISTs without LNM) or the LN+ group (GISTs with LNM). The clinicopathological features and follow-up data were analyzed. Propensity score matching (PSM) was conducted to reduce bias caused by confounders.

Results

Out of 1024 surgical patients, 198 patients (age, 52.23 ± 13.54 years; 56.6% males) underwent GIST resection with l

SUBMITTER: Guo X 

PROVIDER: S-EPMC12140495 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature