Patient-reported gastrointestinal involvement is associated with reduced quality of life and disability in systemic sclerosis.

ABSTRACT:

Objectives

To investigate the impact of gastrointestinal involvement in systemic sclerosis affecting the quality of life and systemic sclerosis-related disability using patient-reported outcome measurements (PROMs).

Methods

Data from 160 consecutive systemic sclerosis patients were collected, including clinical characteristics and self-assessment questionnaires. The severity of gastrointestinal involvement was determined by the University of California Los Angeles Scleroderma Clinical Trials Consortium gastrointestinal tract 2.0 (UCLA-GIT 2.0): patients were classified as having "none-to-mild" symptoms (total score = 0.00-0.49: Group A), "moderate" symptoms (Group B), and "severe-to-very severe" symptoms (Group C). All investigations were repeated following 1 year to check t

SUBMITTER: Keringer P 

PROVIDER: S-EPMC12141260 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature